[Long stabilization of sarcomatoid renal cell carcinoma treated with sorafenib].

نویسندگان

  • M J Juan
  • M Á Climent
چکیده

With regard to the recent article by Husillos et al. on the scarcely prevalent collecting duct renal cancer and due to its histological peculiarity, we want to share our experience with another no less characteristic anatomopathological variant with the readers of Actas Urológicas.1 It is a 65-year-old male who consulted in May 2007 for epigastric pain with mass at that location. He underwent a CT scan which showed large retroperitoneal tumor that depended on the left renal upper pole, as well as multiple pulmonary nodules compatible with metastasis in balloon release (Fig. 1). Given these findings, left radical nephrectomy was carried out. The anatomopathological analysis revealed a renal carcinoma with leiomyo-sarcomatoid differentiation in 90% of the sample, Fuhrman grade IV. It showed positivity immunohistochemically for cytokeratin (AE1/AE3), actin, desmin, and vimentin (Figs. 2 and 3).

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1. Husillos A, Herranz-Amo F, Subirá D, Lledó E, Molina-Escudero R, Hernández-Fernández C. Carcinoma de células renales del túbulo colector. Actas Urol Esp. 2011;35:368--71. 2. Cheville JC, Lohse CM, Zincke H, Weaver AL, Leibovich BC, Frank I, et al. Sarcomatoid renal cell carcinoma: an examination of underlying histologic subtype and an analysis of associations with patient outcome. Am J Surg ...

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عنوان ژورنال:
  • Actas urologicas espanolas

دوره 36 6  شماره 

صفحات  -

تاریخ انتشار 2012